What's actually happening
Uranus takes about 84 years to complete one circuit of the zodiac, spending roughly seven years in each sign. Virgo is a mutable earth sign ruled by Mercury.
What the tradition makes of it
Uranus in Virgo disrupts the practical and the technical. The systems through which work is organized, bodies are maintained, and the fine details of daily function are accomplished — these undergo transformation that is unexpected in its speed and in the degree to which it renders prior practice obsolete.
The tradition notes that Uranus in Virgo tends to coincide with significant advances in medicine and technology at the level of practical application — not the theoretical breakthrough but the sudden availability of what changes how ordinary people work and maintain their health. The disruption is granular and pervasive rather than spectacular.
The shadow is the fragmentation of what required coherence — systems of knowledge and care that are disrupted before their successors are ready to take their place.
How to actually use it
Pay attention to the technical disruptions in your specific domain. This is a period when the tools of the craft change more rapidly than usual, and those who adapt early tend to find themselves ahead of those who adapt late.
Attend to the body's knowledge alongside the system's knowledge. The two do not always agree.
When in doubt
What is the most important thing to actually get right — not theoretically right, but operationally right?